• منطقة بودونغ الجديدة ، شنغهاي ، الصين .
  • [email protected]

Guidelines for the labelling of leucocytes with 111 In-oxine

White blood cells (WBC) labelled with 111 In-oxine ( 111 In-8-hydroxyquinoline) have been successfully applied in the field of infection/inflammation …

اقرأ المزيد

Recruitment of 99hnetium- or 111-indium-labelled …

U.S. Department of Energy Office of Scientific and Technical Information. Search terms: Advanced search options. ...

اقرأ المزيد

111-Indium labelled autologous leucocytes in diagnosis of …

111-Indium labelled leucocytes have been used to visualize inflammatory lesions in ulcerative colitis (CU) and in Crohn's disease (CD). The aim of this study was to compare findings by scintigraphy, radiology and endoscopy. Material: Twelve patients with CU and 15 patients with CD were studied. All patients were non-febrile.

اقرأ المزيد

INDIUM-111-LABELLED LEUCOCYTES FOR LOCALISATION …

Leucocytes from eight patients who were thought to have an abscess were labelled with indium-111 and reintroduced into the circulation. The distribution of radioactivity was followed by wholebody scanning and imaging with a gamma camera. Focal accumulations of radioactivity were observed in the lesion in the three patients with …

اقرأ المزيد

Lack of Clinical Utility of Labeled White Blood Cell Scintigraphy in

The labeled white cells were resuspended in the patient's plasma and sent back to our hospital for immediate reinjection into the patient. Scanning was performed 24 hours later (indium-111) or 2–3 hours later (Tc-99m), as per standard nuclear medicine protocols . Whole-body imaging was performed on a total of 16 Siemens and GE dual …

اقرأ المزيد

Skeletal uptake of indium 111-labeled white blood cells

Segal AW, Arnot RN, Thakur ML, et al: Indium-111 labelled leucocytes for localisation of abscesses. Lancet 2:1056-1057, 1976 32. Thakur ML, Lavender JP, Arnot RN, et al: Indium- 111 labeled autotogous leukocytes in man. J Nucl Med 18:1012-1019, 1977 33. Uno K, Matsui N, Nohira K, et al: Indium-Ill leukocyte imaging in patients with rheumatoid ...

اقرأ المزيد

INDIUM-111-LABELLED LEUCOCYTES FOR LOCALISATION OF ABSCESSES

The indium-111 chelate was prepared by the addition of SO g of oxine to a solution of carrier-free indium-111 (Radioche- mical Centre, Amersham) adjusted to pH 5.6 with 0.3 mo)/t acetate buffer. The complex was extracted into an equal volume of chloroform which was evaporated to dryness in a boiling water-bath.

اقرأ المزيد

Comparison of indium-111 oxinate labelled autologous

Bacterial abscesses were evoked in goats. Imaging of these abscesses was obtained by means of labelling autologous granulocytes with 111 In oxinate, reinjection of the cells into the animal, and scintigraphy by gamma camera one day later. Comparable imaging results, however, were obtained after intravenous injection of 111 In oxinate or of 111 In chloride.

اقرأ المزيد

INDIUM-111 TAGGED LEUCOCYTES IN THE DIAGNOSIS OF

The Lancet INDIUM-111 TAGGED LEUCOCYTES IN THE DIAGNOSIS OF INFLAMMATORY BOWEL DISEASE AnthonyW. Segal J. Michael Munro Jill Ensell Martin Sarner Departments of Haematology, Medical Physics, and Gastroenterology, Faculty of Clinical Sciences, School of Medicine, University College, London WC1, United Kingdon …

اقرأ المزيد

Simultaneous administration of111In-human immunoglobulin …

Technetium-99m hexamethylpropylene amine oxime (HMPAO) labelled leucocytes and indium-111 polyclonal immunoglobulin (IgG) were simultaneously injected into a group of 27 patients routinely referred for the investigation of inflammatory bowel disease (IBD). Ten-minute anterior abdomen and tail on detector views were obtained at 30 min, 4 h and 24 …

اقرأ المزيد

INDIUM-111 TAGGED LEUCOCYTES IN THE DIAGNOSIS OF

The distribution of autologous leucocytes labelled with the gamma-ray emitting radioisotope indium-111 was studied in 25 patients with inflammatory bowel disease, 15 with Crohn's disease, and 10 with ulcerative colitis. In all instances the bowel lesion was identified.

اقرأ المزيد

Guidelines for the labelling of leucocytes with In-oxine

In the mid 1970s, 111In-oxine was introduced as a labelling agent for WBC scintigraphy. The 111In-oxine solution is supplied in a vial as a ready-to-use radiopharmaceutical. Indium …

اقرأ المزيد

Evaluation of white cell scintigraphy using indium-111 and …

Indium-111 oxine labelled leucocyte (111 In oxine leucocyte) scintigraphy is the test of choice in detecting occult infection and localising focal inflammation.111 In oxine labelling is technically difficult and expensive and leucocyte labelling with technetium-99m stannous colloid (99m Tc Sn colloid) has been considered to be an alternative. . Leucocytes from …

اقرأ المزيد

Granulocyte-specific monoclonal antibody technetium-99m-BW

Thirty-three patients suspected of suffering from inflammatory bowel disease were studied. Autologous leucocytes were labelled with indium 111 oxine and re-injected simultaneously with 0.3–0.5 mg of technetium 99m granulocyte-specific monoclonal antibody BW 250/183. Two scans were obtained, the early scan 3–4 h postinjection (p.i.) and the late scan …

اقرأ المزيد

In-111 labeled leukocytes: a review of problems in image …

Leukocyte suspensions labeled with In-111 oxine or tropolone were administered intravenously to 150 patients for the detection of suspected foci of bacterial infection by gamma camera imaging. The results were correlated with other imaging modalities, and clinical, laboratory, and surgical findings after a minimum follow-up period of six months. …

اقرأ المزيد

Sethna SAVERYMUTTU | Mid Essex Hospital Services NHS

The value of indium-labelled leucocytes in clinical practice. Article. ... Indium 111-leukocyte scanning has recently been introduced as a new method for imaging inflammatory bowel disease. The ...

اقرأ المزيد

111 Indium-Labeled Leukocyte Imaging of Infection and Inflammation

111Indium-Labeled Leukocyte Imaging of Infection and Inflammation Sara K. Meibom4, Ilan Y. Benador-Shen5& Gustavo A. Mercier4 Chapter First Online: 25 …

اقرأ المزيد

Indium-111-labelled leucocytes in the diagnosis of abdominal …

The extensive morbidity and mortality of intra-abdominal abscess is mainly due to the delay in a diagnosis. The diagnostic accuracy of 111 In-labelled mixed leucocytes with gamma imaging has been investigated in 100 consecutive patients including 34 following surgery and 36 with inflammatory bowel disease. White cell scans were performed 24 h following …

اقرأ المزيد

Limitations in the use of indium-111-oxine-labeled leucocytes for …

247 17 17 2 2 M. Haentjens A. Piepsz E. Schell-Frederick N. Perlmutter-Cremer J. Frühling Departments of Paediatrics, Radioisotopes and Radiology Saint-Pierre Hospital, Free Universities (ULB, VUB) of Brussels Belgium Medizinische Universitätsklinik Cologne FRG Department of Radiotherapy, Radioisotope Laboratory Institut J. Bordet, …

اقرأ المزيد

Leucocyte scanning: Preparation and labelling of leucocytes with 111

A method for the concentration of leucocytes from blood and labelling of the separated cells with 111-Indium oxine is described. This method guaranteed a good preparation. On average there were 64.8% of leucocytes from the blood in the concentrate. The yield of the labelling averaged 93%. Seventy-two patients from various departments were examined …

اقرأ المزيد

Scintigraphic evaluation of the painful prosthetic

The radiopharmaceuticals gallium-67 and indium-111 labelled leucocytes have been compared in 15 patients with a painful joint prosthesis in an attempt to identify those patients with periprosthetic infection. Gallium-67 images were abnormal in five out of six patients with periprosthetic infection and normal in seven out of nine without ...

اقرأ المزيد

Indications des scintigraphies au Gallium 67 et aux leucocytes …

A prospective scintigraphic study using Gallium 67 and granulocytes labelled with Indium 111 was carried out in 60 patients who were thought to have infection following orthopaedic operations. Both investigations gave positive results in 11 of the 16 infections observed. The Indium 111 labelled leucocyte scan was more accurate than the Gallium 67 studies in …

اقرأ المزيد

Method for labelling leucocytes with indium In-111 oxine

OSTI.GOV. Patent: Method for labelling leucocytes with indium In-111 oxineMethod for labelling leucocytes with indium In-111 oxine

اقرأ المزيد

Indium-111-labelled leucocytes for localisation of abscesses

Leucocytes from eight patients who were thought to have an abscess were labelled with indium-111 and reintroduced into the circulation. The distribution of radioactivity was followed by whole-body scanning and imaging with a gamma camera. Focal accumulation of radioactivity were observed in the lesi …

اقرأ المزيد

Guidelines for the labelling of leucocytes with 99mTc …

leucocytes or isolated granulocytes can be used. When mixed leucocytes are labelled with99mTc-HMPAO, about 70–80% of the radioactivity is bound to granulocytes. Labelled mixed leucocytes can display higher blood pool activity than labelled isolated granulocytes, especially in early images, due to the presence of labelled lymphocytes

اقرأ المزيد

Imaging of bone infection with labelled white blood cells role of

Mulamba L'AH, Ferrant A, Leners N, De Nayer P, Rombouts JJ, Vincent A (1983) Indium-111 leucocyte scanning in the evaluation of painful hip arthroplasty. Acta Orthop Scand 54:695–697. Google Scholar Peters AM, Saverymuttu SH (1987) The value of indium labelled leucocytes in clinical practice. Blood Rev 1:65–76

اقرأ المزيد

Clinical Utility of Indium 111–Labeled White Blood Cell …

Keywords: leukocyte scintigraphy, nuclear imaging, prosthetic graft infection, osteomyelitis. Indium 111 ( 111 In)–labeled white blood cell (WBC) scintigraphy is an …

اقرأ المزيد

111Indium autologous leucocytes in inflammatory bowel disease.

Indium-111-labelled leucocytes for localisation of abscesses. Lancet. 1976 Nov 13; 2 (7994):1056–1058. [Google Scholar] Ascher NL, Ahrenholz DH, Simmons RL, Weiblen B, Gomez L, Forstrom LA, Frick MP, Henke C, McCullough J. Indium 111 autologous tagged leukocytes in the diagnosis of intraperitoneal sepsis. Arch Surg. 1979 Apr; 114 (4):386–392.

اقرأ المزيد

Leukocyte in 111

Indium-111 leukocytes are taken up nonspecifically in sites of inflammation, inciting a leukocytic response, regardless of the presence or absence of infection (Box 12-1). The …

اقرأ المزيد

Indium-111-labeled autologous leukocyte imaging and fecal

Segal AW, Ensell J, Munro JA, Sarner M: Indium-111 tagged leucocytes in the diagnosis of inflammatory bowel disease. Lancet 2:230–232, 1981. Google Scholar Saverymuttu SH, Peters AM, Chadwick VS, Hodgson HJ, Lavender JP: Imaging diseased bowel with indium-111 labeled leucocytes. Br J Radiol 54:707, 1981

اقرأ المزيد

Pulmonary Activity on Labeled Leukocyte Images: Physiologic, …

Pulmonary uptake in indium-111 leukocyte imaging: clinical significance in patients with suspected occult infections. Radiology 1984; 150:557-561. Link, Google Scholar; 2 Seabold JE, Wilson DG, Lieberman LM, Boyd CM. Unsuspected extra-abdominal sites of infection: scintigraphic detection with indium-111-labeled leukocytes. Radiology …

اقرأ المزيد

Leucocyte scanning—a valuable tool in diagnosing cerebral

Peters AM (1980) Diagnosing cerebral abscess with In-111 labelled leucocytes. Lancet (letter) August 2 (8199): 309–310. Google Scholar Rehncrona S, Brigmar J, Holtes S (1985) Diagnosis of brain abscesses with Indium-111-labelled leucocytes. Neur Surg 16: 23–26. Google Scholar

اقرأ المزيد

Indications des scintigraphies au Gallium 67 et aux …

Le marquage des leucocytes ~ l'Indium 111 s'est effectu~ selon la m6thode d~crite par Mc Afee [4]. Nous avons utilis~ le test d'Agarose de Cuttler [2] pour ~valuer la conservation du ch~- motactisme leucocytaire. Le test au bleu Trypan a permis de compter les leucocytes d&ruits au eours du marquage.

اقرأ المزيد

Granulocyte-specific monoclonal antibody technetium-99m-BW …

Autologous leucocytes were labelled with indium 111 oxine and re-injected simultaneously with 0.3-0.5 mg of technetium 99m granulocyte-specific monoclonal antibody BW 250/183. Two scans were obtained, the early scan 3-4 h postinjection (p.i.) and the late scan 18-24 h p.i. Using the endoscopy study as standard, the diagnostic accuracy of both ...

اقرأ المزيد

The value of indium-labelled leucocytes in clinical practice

Following intravenous injection, autologous 111 In labelled-leucocytes migrate to sites of inflammation, where they can be imaged with the gamma camera. The principle underlining the labelling technique is exposure of a population of leucocytes or purified granulocytes to a lipophilic 111 In complex, such as 111 In oxine or 111 In tropolonate. As …

اقرأ المزيد

Indium-111 labelled white blood cell scintigraphy in cranial

This study aimed to evaluate the accuracy of indium-111 white blood cell (WBC) scan in assessing the presence of leucocytes in intracranial and spinal lesions, and in the diagnosis, management and follow-up of primary, post-traumatic and post-surgical infections. One hundred and twenty-four subjects were included in the study (48 with post ...

اقرأ المزيد